VThunter
a database for single-cell screening of virus target cells in animal kingdom
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Human

Scientific Name: Homo sapiens

Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Euarchontoglires-> Primates-> Haplorrhini-> Simiiformes-> Catarrhini-> Hominoidea-> Hominidae-> Homininae-> Homo

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Respiratory syncytial virus

Family: Pneumoviridae

Receptor: CLEC4M

Receptor CLEC4M information

Summary: This gene encodes a C-type lectin that functions in cell adhesion and pathogen recognition. This receptor recognizes a wide range of evolutionarily divergent pathogens with a large impact on public health, including tuberculosis mycobacteria, and viruses including Ebola, hepatitis C, HIV-1, influenza A, West Nile virus and the SARS-CoV acute respiratory syndrome coronavirus. The protein is organized into four distinct domains: a C-terminal carbohydrate recognition domain, a flexible tandem-repeat neck domain of variable length, a transmembrane region and an N-terminal cytoplasmic domain involved in internalization. This gene is closely related in terms of both sequence and function to a neighboring gene, CD209 (Gene ID: 30835), also known as DC-SIGN. The two genes differ in viral recognition and expression patterns, with this gene showing high expression in endothelial cells of the liver, lymph node and placenta. Polymorphisms in the tandem repeat neck domain are associated with resistance to SARS infection. [provided by RefSeq, May 2020] [NCBI]  [Proteinatlas]

Data Source

Data set information

Project Date Technology Tissue Condition Cell PMID/DOI
Vthunter_100013 2020.03 Microwell-seq Adult AdrenalGland Normal 8114 Link
Vthunter_100014 2020.03 Microwell-seq Adult AdrenalGland Normal 15083 Link
Vthunter_100023 2020.03 Microwell-seq Adult Colon Normal 5765 Link
Vthunter_100027 2020.03 Microwell-seq Adult Esophagus Normal 8668 Link
Vthunter_100028 2020.03 Microwell-seq Adult Fallopiantube Normal 6556 Link
Vthunter_100029 2020.03 Microwell-seq Adult Gallbladder Normal 9769 Link
Vthunter_100033 2020.03 Microwell-seq Adult Ileum Normal 3367 Link
Vthunter_100034 2020.03 Microwell-seq Adult Jejunum Normal 5549 Link
Vthunter_100035 2020.03 Microwell-seq Adult Kidney Normal 9153 Link
Vthunter_100036 2020.03 Microwell-seq Adult Kidney Normal 9966 Link
Vthunter_100037 2020.03 Microwell-seq Adult Kidney Normal 3849 Link
Vthunter_100038 2020.03 Microwell-seq Adult Liver Normal 1811 Link
Vthunter_100039 2020.03 Microwell-seq Adult Liver Normal 4377 Link
Vthunter_100040 2020.03 Microwell-seq Adult Liver Normal 4384 Link
Vthunter_100041 2020.03 Microwell-seq Adult Lung Normal 8426 Link
Vthunter_100042 2020.03 Microwell-seq Adult Lung Normal 6022 Link
Vthunter_100046 2020.03 Microwell-seq Adult Omentum Normal 9971 Link
Vthunter_100057 2020.03 Microwell-seq Adult Spleen Normal 15806 Link
Vthunter_100059 2020.03 Microwell-seq Adult Stomach Normal 4669 Link
Vthunter_100063 2020.03 Microwell-seq Adult Thyroid Normal 6328 Link
Vthunter_100067 2020.03 Microwell-seq Adult Uterus Normal 7694 Link
Vthunter_100068 2020.03 Microwell-seq ChorionicVillus Normal 9898 Link
Vthunter_100073 2020.03 Microwell-seq Fetal AdrenalGland Normal 9875 Link
Vthunter_100074 2020.03 Microwell-seq Fetal AdrenalGland Normal 2547 Link
Vthunter_100075 2020.03 Microwell-seq Fetal AdrenalGland Normal 1994 Link
Vthunter_100082 2020.03 Microwell-seq Fetal FemaleGonad Normal 2710 Link
Vthunter_100083 2020.03 Microwell-seq Fetal FemaleGonad Normal 4231 Link
Vthunter_100085 2020.03 Microwell-seq Fetal Heart Normal 2678 Link
Vthunter_100088 2020.03 Microwell-seq Fetal Intestine Normal 9740 Link
Vthunter_100091 2020.03 Microwell-seq Fetal Kidney Normal 4939 Link
Vthunter_100092 2020.03 Microwell-seq Fetal Kidney Normal 4734 Link
Vthunter_100093 2020.03 Microwell-seq Fetal Kidney Normal 9932 Link
Vthunter_100094 2020.03 Microwell-seq Fetal Kidney Normal 3057 Link
Vthunter_100095 2020.03 Microwell-seq Fetal Liver Normal 17929 Link
Vthunter_100096 2020.03 Microwell-seq Fetal Lung Normal 4526 Link
Vthunter_100098 2020.03 Microwell-seq Fetal MaleGonad Normal 3358 Link
Vthunter_100099 2020.03 Microwell-seq Fetal MaleGonad Normal 9853 Link
Vthunter_100101 2020.03 Microwell-seq Fetal Pancreas Normal 8977 Link
Vthunter_100102 2020.03 Microwell-seq Fetal Pancreas Normal 6939 Link
Vthunter_100103 2020.03 Microwell-seq Fetal Pancreas Normal 2830 Link
Vthunter_100109 2020.03 Microwell-seq Fetal Stomach Normal 1322 Link
Vthunter_100114 2020.03 Microwell-seq NeonatalAdrenalGland Normal 5863 Link
Vthunter_100115 2020.03 Microwell-seq Placenta Normal 9595 Link
Vthunter_110062 2020.07 10X Genomics Lung Normal 31644 Link
Vthunter_110063 2019.12 10X Genomics Blood Normal 94257 Link
Vthunter_110065 2019.12 MARS-seq BrainCortex Normal 2304 Link
Vthunter_110077 2020.01 10X Genomics Spleen Normal 94257 Link
Vthunter_110078 2018.12 10X Genomics Placenta Normal 16075 Link
Vthunter_110079 2018.09 10X Genomics Liver Normal 8444 Link
Vthunter_110080 2020.05 10X Genomics Lung Disease 57299 Link
Vthunter_110088 2018.12 10X Genomics Decidua Normal 34072 Link
Vthunter_110089 2018.12 10X Genomics Blood Normal 9558 Link
Vthunter_110093 2019.05 10X Genomics AnteriorCingulateCortex Normal 22409 Link
Vthunter_110094 2019.05 10X Genomics PrefrontalCortex Normal 30147 Link
Vthunter_110100 2020.09 10X Genomics Teeth Teeth 41673 Link
Vthunter_110102 2018.08 10X Genomics Testis Testis 6199 Link
Vthunter_110103 2019.05 10X Genomics FoveaRetina FoveaRetina 2811 Link
Vthunter_110104 2020.09 10X Genomics Endometrium Endometrium 71032 Link
Vthunter_110108 2021.04 10X Genomics Cornea Cornea 21343 Link
Vthunter_110109 2019.05 10X Genomics FoveaRetina FoveaRetina 767 Link
Vthunter_110110 2019.05 10X Genomics PeripheralRetina PeripheralRetina 2924 Link
Vthunter_110111 2019.05 10X Genomics PeripheralRetina PeripheralRetina 1715 Link
Featureplot of receptors

Featureplot of receptors

mRNA expression of CLEC4M in human tissues   [NCBI]

Expression: Biased expression in liver (RPKM 15.4), lymph node (RPKM 9.8) and 3 other tissues?

Protein expression of CLEC4M in human tissues   [Proteinatlas]